Potential application:

  • Protein crystal
  • Peptide crystal 
  • Inorganic crystal 
  • Small molecule crystal 

Primary microscope to use:

  • Talos Artica 200 KeV with DE-64 camera 
  • Titan Krios 300 KeV with CetaD camera

Preliminary screening microscopes:

  • JEOL 1200 

Cryo-FIB:

  • FEI Aqulios 2

Pipeline:

  1. Choose appropriate sample preparation method to prepare EM grid
  2. Preliminary screening, identify potential crystal size and crystalline order 
  3. Perform cryo-FIB or FIB if necessary 
  4. Data collection at Talos microscope 





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